If someone enters as competitor because of high prices/profit, they'll want for them to stay that way. It won't make it better for the consumer if the supply is constricted in such a way.
I think this is a point where governments should intervene and perhaps start fabs that would produce RAM at cost for working class and SMEs to use.
Would be really nice honestly. But I don't think it will be coming anytime soon, it's just too expensive to build a chip.
The one-time costs for masks are just much more expensive as for PCBs, so wafer shuttle services are still really expensive when pooled PCBs are really cheap.
And any machines that would be cheaper for prototyping (direct laser writing or direct e-beam writing) don't scale to mass production.
You can already make (tiny) chips for a somewhat affordable cost with tiny tapeout.
But that's still not nearly as cheap as PCB prototypes and with much longer wait times.
Even if we assume your body has a foolproof is_same_species() test, your neighbors' cells may:
1. Be healthy, but have the wrong priorities or behavior, so that they start doing the wrong tasks or sending the wrong messages in the wrong places. [0]
2. Be healthy, but they're just a creepy flesh-mask a parasite has constructed around itself.
3. Be individually hijacked by viruses, and your body won't have the same baseline information to tell that they've deviated from your neighbor's standard.
4. They may be fully human, but gone feral into a transmissible tumor [1].
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[0] This is actually a risk from pregnancy, as overambitious fetal cells leak into the mother.
In this case nature was just indifferent to transplants as they weren't a thing even 100 years ago.
As others have explained, foreign cells usually meant trouble, so fighting them by default was a good choice. And there was no pressure to allow transplants specifically, because they didn't exist.
Also, (I think) you usually need a transplant later in life, after reproduction, so too late for evolution to affect it. So even if we had transplants for millions of years, it might not have made much difference either.
I'm a kidney transplant patient myself. Your cells have HLA markers to distinguish your own cells from foreign cells. That is to prevent your immune cells from attacking your own body. This also makes it harder to find a organ match.
The reason I needed a kidney transplant is because of an auto disease called IgA Nephropathy where the IgA antibody has a small defect that causes the rest of the immune system to attack it and the whole mess clogs up the kidney filters over time.
There is zero inherent way to tell a malicious group of proteins and RNA or cells or biological process from a non-malicious once. They are both the same exact activity. Your body is killing cells all the time, so even cell death isn't a certain indicator (though is an indicator in the innate immune system and cells dying the "wrong" way will activate a response)
The only useful signal is "This wasn't here yesterday". Your body generates B cells with a little sensor that has it's own special systems to have especially randomized sensor activity. Your body is generating random binding sites because there's no rules for what a hostile protein would look like.
Then it prunes these B cells by showing them a bunch of proteins your body is capable of producing, and killing any cell that signals for proteins your body normally has. This leaves you with a bunch of B cells that have random sensors tuned to only trigger for things that weren't in your body yesterday.
This is great, because it's a proactive measure against evolution. It's the core innovation of the adaptive immune system, and a massive advancement in biological self defense.
Cells from someone else will have some different markers and proteins than found in your body. Human genetics are 99% the same yes, but there is massive diversity in the remainder.
Note that this constraint is not biological in nature! Any general purpose "programming" environment cannot differentiate between "Hostile" and "Benign" by function or structure alone! The body, like many smart cybersecurity groups, made an allowlist. Though the way that allowlist is made is fascinating
The way your body detects foreign cells is the same way your body detects foreign cells. It detects anything that doesn't have your, specific, randomly-generated at conception, friend-or-foe markers.
In all these cases cells that are "other than your own" are in your system and need to be eliminated, in the case of cancer it's your own cells but with significant mutations, as far as I can tell there is always an immune response although in some cases it is actually counter productive.
Since Epstein is no more, the governments became crazy about going after people's private data, perhaps hoping to find some spice. Like some politicians lost their source.
I think this is a point where governments should intervene and perhaps start fabs that would produce RAM at cost for working class and SMEs to use.
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