Well let's not forget Zigzag. This is hyperstructure and Ted's greatest achievement. If you want to try it out, Gzz 0706.jar runs on Java https://www.nongnu.org/gzz/download.html

I think NTFS and SSD disks.

Fragmentation is an issue with any file system. SSDs dramatically reduce the cost of fragmentation but do not eliminate it, as non-sequential access is still slower than sequential access.

I like the comment on the site about blockchains replacing HTML links (from 4 years ago).