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Barbituate withdrawal won’t kill you.

Benzodiazepines, and alcohol, can actually induce death if you withdraw too quickly


Barbiturate withdrawal can absolutely kill you, as it is the same process of benzodiazepines and alcohol withdrawals. The other issue is that barbiturates themselves can easily kill you due their MOA, and low therapeutic index

Didn’t Cringely pass away recently?


According to a HN post, and basically nothing else that I can seem to find.

Who knows, maybe he's still alive and posted the death notice himself. Dude is/was a compulsive liar. There's still to this day no actual evidence that he genuinely has passed away (unless I'm just unable to find it)



This post is also dated in July, which would have been before he passed away if that post was accurate.


when the author mentioned playing prince of persia on a pc-xt, i assumed this was some kind of ai-generated nonsense

but no

they actually did port the game to the lowest-end hardware available in 1989. you could actually play prince of persia on an 8088 with a cga card!


Just about every PC game in 1989 ran on an XT with CGA.


The XT came out in 1983, it was a real piece of shit by 1989 standards

Not to mention, the PC was a pretty, uh, "challenging" platform for video games. It amazes me someone managed to port something as graphically sophisticated as PoP to an 8088 with CGA.


PCs were incredibly expensive at the time, though, and barely useful. Most people didn't buy a new one every two years, despite the fast progress in hardware development. So many people, especially kids, were stuck with "ancient" hardware. I had friends who had an 8088 PC or an Apple II in the late 90s.


The XT was significantly more powerful than the Apple II in every way except color depth.


Specifically, no one will earn a promotion by talking to another team or improving customer service


Anxiety is a common comorbidity in depression patients and buprioprion can dramatically raise anxiety levels

It is a second-line treatment for a reason. Great when it works. Harmful when it does not.


Yeah, this is exactly why I couldn’t stay on it. I already deal with GAD and OCD, and whatever benefits it had for the depression were directly counteracted by the return of acute anxiety.

It was truly hellish. Feeling like I had this energy that I needed to use, while also feeling so anxious that I didn’t want to leave the apartment.

I know it works really well for some people but I was definitely not one of them.


Thank you, that answer makes a lot of sense.


Just want to underscore that this is the right answer.


turns out there is more involved in performance than just clock rate

who knew? (everyone)


And the Alpha was faster

The last line of the parent post makes it sound as if the chips didn't exist at the same time.


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