My most likely doom scenario is that a frontier model convinces the CIC to press the nuclear retaliation button. Maybe this will only kill 90% of humans, but as far as I am concerned, that’s good enough.
If the Commander In Chief is that gullible we are already doomed. Under that logic we should stop having babies in case selection results in a "superpersuader" capable of convincing the president to launch the nukes unbidden.