So much for a good faith discussion here. I don't appreciate that you tell me to "get a grip". You're not steelmanning. Instead, your reaction comes off as a knee jerk reaction. There are enough communities where I have to come up with defenses to deal with that nonsense. Don't do it here please.
US melatonin measured dosage can be 4x as much as what is reported [1, 2].
Also 0.3 mg is the recommended dose [4]. A lot of doses in the US are way higher than 0.3 mg. In the Netherlands it's stupidly easy to find 0.1 mg doses (e.g. at the Kruidvat or at the Etos). It's in part why I never looked further.
And since you're new here (55 days ago, 13 karma as of writing). I strongly recommend you to read the HN guidelines [3]. All people who are on HN should follow them, not knowing them degrades the community experience that we're having here.
> Be kind. Don't be snarky. Converse curiously; don't cross-examine. Edit out swipes.
> Comments should get more thoughtful and substantive
There are a few others that apply as well.
[1] Cohen PA, Avula B, Wang YH, Katragunta K, Khan I. Quantity of Melatonin and CBD in Melatonin Gummies Sold in the US. JAMA. 2023;329(16):1401–1402. doi:10.1001/jama.2023.2296
(referring to melatonin) yeah this is valid. I used to take melatonin every night, found out about the problems with us supply, couldn't find anything nearing 1/2 mg, and gave up. I took kids gummies for a few weeks, but I still think they were 1mg.
I can Google very well. The smallest dosages I found were 0.5 and 0.25 for kids (against AAP advice!)
The discussion was about 0.1 for finer grained control and implied ability to experiment with dosages rather than stick with third party selected dosage regardless of needs.
> You literally said you can't trust the US for this. Okay.
Refute my sources, I gave you sources. You're ignoring it. If you're ignoring the studies I provide, why have a discussion at all?
I've been getting melatonin at 0.1 mg for the past 15 years in the Netherlands. I first got wind that it was different in the US on a Huberman podcast. He got it from studies. I cited some.
Pharma and Healthcare was the implication I believe. The US approach to these things has a bad reputation internationally though I am informed that it’s an amazing system if you’re rich.
Let’s not conflate US pharma with their healthcare more generally.
The US is dominant in pharmaceutical and biotech, and FDA is generally excellent as a regulator, despite (IMO) sometimes being too conservative and resistant to any ideas not gestated within the agency. There are weird quirks (like the wide and wacky dosages of melatonin available over the counter, in this example) but most countries have such quirks.
US melatonin measured dosage can be 4x as much as what is reported [1, 2].
Have you never looked into stuff like this? It's all over social media and the claims are relatively easy to verify. I'm asking because I need to know if I'm in a bubble or not.
[1] Cohen PA, Avula B, Wang YH, Katragunta K, Khan I. Quantity of Melatonin and CBD in Melatonin Gummies Sold in the US. JAMA. 2023;329(16):1401–1402. doi:10.1001/jama.2023.2296
